Amustaline (S-303) dihydrochloride, a nucleic acid-targeted alkylator, is an efficient pathogen inactivation agent for blood components containing red blood cells. Amustaline dihydrochloride has three components: an acridine anchor (an intercalator that targets nucleic acids non-covalently), an effector (a bis-alkylator group that reacts with nucleophiles), and a linker (a small flexible carbon chain containing a labile ester bond that hydrolyzes at neutral pH to yield non-reactive breakdown products) .
EC Number: 691-299-2
PubChem CID: 6433103
Isomeric SMILES: C1=CC=C2C(=C1)C(=C3C=CC=CC3=N2)NCCC(=O)OCCN(CCCl)CCCl.Cl.Cl
- UPC:
- 51101618
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A973186-1mg
- Product Size:
- 1mg
- CAS:
- 210584-54-6
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