AMIKACIN SULFATE 1:2 (C005B-038513)

General description

Chemical structure: aminoglycoside

Application

Amikacin is an aminoglycoside antibiotic commonly used in the treatment of drug-resistant mycobacteria . It is used to study organism-directed delivery of antibiotics as well as drug resistance .

Biochem/physiol Actions

Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Molecular Weight: 781.76. Empirical Formula: C₂₂H₄₃N₅O₁₃ · 2H₂SO₄. biological source: synthetic. Quality Level: 200. form: powder or crystals. potency: 674-786 . μ. g per mg (as amikacin base). color: white to off-white. antibiotic activity spectrum: Gram-negative bacteria, mycobacteria. Mode of action: protein synthesis | interferes. storage temp.: 2-8°C. SMILES string: OS(O)(: O): O.OS(O)(: O): O.NCC[C@H](O)C(: O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O. InChI: 1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21. 2*1-5(2,3)4/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36). 2*(H2,1,2,3,4)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+. . /m0../s1. InChI key: FXKSEJFHKVNEFI-GCZBSULCSA-N. Pictograms: GHS07,GHS08. Signal Word: Warning. Hazard Statements: H317 - H361fd. Precautionary Statements: P202 - P261 - P272 - P280 - P302 + P352 - P308 + P313. Hazard Classifications: Repr. 2 - Skin Sens. 1. Storage Class Code: 11 - Combustible Solids. WGK: WGK 2. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).