ECDYSONE (C005B-035749)

General description

α-Ecdysone is a phytoecdysteroid, synthesized from cholesterol, and one of the major insect molting hormones. Ecdysone is secreted by the ecdysial glands present in insects.

Application

α-Ecdysone has been used:

• to study its effects on Drosophila melanogaster′s sexual maturation
• to study its effects on specification of neurons in Drosphila male-specific neurite
• as a standard to evaluate the ecdysteroid levels by liquid chromatography-mass spectrometry (LC-MS/MS)

Biochem/physiol Actions

Ecdysone exerts its effects via the ecdysone receptor and regulates larval molting, reproduction, and metamorphosis in insects.

Molecular Weight: 464.63. Empirical Formula: C₂₇H₄₄O₆. sterility: non-sterile. Quality Level: 200. Assay: ≥. 90%. form: powder. solubility: methanol: 20 . mg/mL, clear, colorless to faintly yellow. application(s): agriculture
environmental. shipped in: ambient. storage temp.: −. 20°C. SMILES string: [H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1: CC(: O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@H](C)[C@H](O)CCC(C)(C)O. InChI: 1S/C27H44O6/c1-15(20(28)8-9-24(2,3)32)16-7-11-27(33)18-12-21(29)19-13-22(30)23(31)14-25(19,4)17(18)6-10-26(16,27)5/h12,15-17,19-20,22-23,28,30-33H,6-11,13-14H2,1-5H3/t15-,16+,17-,19-,20+,22+,23-,25+,26+,27+/m0/s1. InChI key: UPEZCKBFRMILAV-JMZLNJERSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).