Gallein is a cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Gallein is reported to exhibit prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model. Gallein is an inhibitor of G β and G γAn inhibitor of Gβγ-dependent cellular activities which binds to Gβγ with high affinity.
Specifications and Purity: ≥85%(HPLC)
MDL Number: MFCD00041839
Molecular Formula: C20H12O7
Molecular Weight: 364.3
PubChem CID: 73685
Isomeric SMILES: C1=CC=C2C(=C1)C(=O)OC23C4=C(C(=C(C=C4)O)O)OC5=C3C=CC(=C5O)O
Beilstein Registry Number: 19(3/4)3147
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/A116396-SCI_5050d0d95c190b3f9ccd0eae8317fa27.pdf
- UPC:
- 12171503
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A116396-100g
- CAS:
- 2103-64-2
- Product Size:
- 100g
akash.verma@cenmed.com
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