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alizarin

Alizarin (C007B-020228)

Catalog No.
C007B-020228
Manufacturer No.
A408093-1ml
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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InformationAlizarin (Anthraquinonic) strongly inhibits P450 isoform CYP1A1, CYP1A2 andCYP1B1withIC50of 6.2 μM, 10.0 μM and 2.7 μM, respectively: weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5.In vitroAlizarin

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InformationAlizarin (Anthraquinonic) strongly inhibits P450 isoform CYP1A1, CYP1A2 andCYP1B1withIC50of 6.2 μM, 10.0 μM and 2.7 μM, respectively; weakly inhibits CYP2A6 and CYP2E1, and does not inhibit CYP2C19, CYP3A4 and CYP3A5.In vitroAlizarin weakly inhibits CYP2A6 and CYP2E1. Alizarin shows competitive inhibition against CYP1B1 with Ki of 0.5 μM. Alizarin reduces the mutagenicity of MeIQx, which induced by each CYP1A2 or CYP1B1, while does not effectively reduce the mutation induced by B[a]P. Alizarin exhibits antioxidants against iodophenol-derived phenoxyl radicals, superoxide anion radicals and lipid peroxidation in rat liver microsomes.In vivoAlizarin also reduces the hepatic content of thiobarbituric acid-reactive substances and the serum level of alanine aminotransferase in poisoned animals.Cell Datacell lines：Concentrations：Incubation Time：Powder Purity:≥97%.

Specifications and Purity: 10mM in DMSO

Molecular Formula: C14H8O4

Molecular Weight: 240.21

UPC:
85000000
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
A408093-1ml
CAS:
72-48-0
Product Size:
1ml

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