ALE-0540, a nonpeptidic small molecule, is a nerve growth factor receptor antagonist. ALE-0540 inhibits the binding of NGF to tyrosine kinase ( Trk ) A or both p75 and TrkA with IC 50 values of 5.88 μM and 3.72 μM, respectively. ALE-0540 can be used to examine mechanisms leading to the development of agents for the treatment of pain .
Specification: ≥98%
PubChem CID: 2826530
Isomeric SMILES: C1=CC2=CC(=CC3=C2C(=C1)C(=O)N(C3=O)NCCO)[N+](=O)[O-]
- UPC:
- 85100000
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A1351387-10mg
- Product Size:
- 10mg
- CAS:
- 234779-34-1
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