ALBUMIN HUMAN RECOMBIANT EXPRESSED IN PICHIA PASTORIS (C005B-057973)

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Physical properties

Recombinant construct with N-terminal deletion of Asp. Structurally equivalent to native albumin by x-ray crystallography. The N-terminal Asp is the principal Cu²⁺ and Ni²⁺ chelation site; its deletion eliminates an important antigenic determinant, and the protein is hypoallergenic. Also blocked at Cys³⁴ to improve stability, monomer content and homogeneity.

Physical form

Solution in phosphate buffered saline containing 4 mM sodium caprylate and 4 mM N-acetyltryptophan.

Other Notes

View more information on human serum albumin.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.

biological source: human. Quality Level: 200. recombinant: expressed in Pichia pastoris. Assay: ≥. 90% (SDS-PAGE). form: solution. mol wt: monomer ~67 . kDa. concentration: 5% in aqueous buffer. technique(s): cell culture | mammalian: suitable. UniProt accession no.: P02768. shipped in: wet ice. storage temp.: 2-8°C. InChI: 1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11. InChI key: QYSGYZVSCZSLHT-UHFFFAOYSA-N. Gene Information: human ... ALB(213). Storage Class Code: 12 - Non Combustible Liquids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.