ACY-957 is an orally active and selective inhibitor of HDAC1 and HDAC2 , with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9In VitroACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC 50 s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC 50 of 304 nM for HDAC2 in primary hematopoietic progenitors. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:HDAC1 7 nM (IC 50 ) HDAC2 18 nM (IC 50 ) HDAC3 1300 nM (IC 50 ).
Specifications and Purity: ≥99%
Molecular Formula: C24H23N5OS
Molecular Weight: 429.54
- UPC:
- 85121705
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A650992-100mg
- CAS:
- 1609389-52-7
- Product Size:
- 100mg
akash.verma@cenmed.com
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