Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK TFA/tsignificantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate (IDB; HY-137295). Ac-DEVD-CMK TFA can be used in a varietAppearance:SolidIn Vitro:Ac-DEVD-CMK TFA (100 μM; 24 h) inhibits IDB-induced apoptosis. Ac-DEVD-CMK TFA inhibits (10 μM; 36 h) inhibits citrate (10 mM)-induced p21 cleavage and G2/M accumulation in human pharyngeal squamous carcinoma FaDu and Detroit 562 cell lines. MCEIn Vivo:Ac-DEVD-CMK TFA (Caspase-3 Inhibitor III; 25mg/kg; IP; single dose; 3 hours post-APAP) significantly attenuates Acetaminophen (APAP; HY-66005)-induced liver injury (AILI). Ac-DEVD-CMK TFA (25mg/kg; ip; single dose) significantly attenuates APAP-indBiological Activity:Ac-DEVD-CMK (Caspase-3 Inhibitor III) TFA is a selective and irreversible caspase-3 inhibitor. Ac-DEVD-CMK TFA/tsignificantly inhibits apoptosis induced by high levels of glucose or 3,20-dibenzoate (IDB; HY-137295). Ac-DEVD-CMK TFA can be used in a variet.
Specifications and Purity: ≥98%
Molecular Formula: C23H32ClF3N4O13
Molecular Weight: 664.97
- UPC:
- 12141801
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- A658802-5mg
- CAS:
- 285570-60-7
- Product Size:
- 5mg
akash.verma@cenmed.com
(732) 447-1115





