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a-803467

A-803467 (C007B-005708)

Catalog No.
C007B-005708
Manufacturer No.
A127941-10mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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A-803467 inhibits spontaneous and evoked action potentials in sensory neurons. It exhibits antinociceptive effects.A-803467 decreases the firing in spinal dorsal horn neurons in vivo.The small molecule A-803467 is a potent and selective Nav1.8

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A-803467 inhibits spontaneous and evoked action potentials in sensory neurons. It exhibits antinociceptive effects.A-803467 decreases the firing in spinal dorsal horn neurons in vivo.The small molecule A-803467 is a potent and selective Nav1.8 sodium channel blocker. Nav1.8 is a tetrodotoxin-resistant (TTX-R) sodium channel that contributes to pain sensation by transmitting pain stimuli in peripheral sensory neurons; blockage of this channel by A-803467 reduces pain with varying effectiveness in a number of different models.A-803467 has been used to further understand the role of Nav1.8 in transmitting pain stimuli and also can be used as an analgesic.

Specifications and Purity: ≥98%

MDL Number: MFCD10574689

Molecular Formula: C19H16ClNO4

Molecular Weight: 357.79

PubChem CID: 16038374

Isomeric SMILES: COC1=CC(=CC(=C1)NC(=O)C2=CC=C(O2)C3=CC=C(C=C3)Cl)OC

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/A127941-SCI_e65d2bc4dbc677abae7c36b0c8f1e3aa.pdf

UPC:
41113107
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
A127941-10mg
CAS:
944261-79-4
Product Size:
10mg
Hazard Statement Codes:
H302
Precautionary Statement Codes:
P501:P301+P312:P330:P270:P264

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