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8-iso prostaglandin e2

8-iso Prostaglandin E2 (C007B-196161)

Catalog No.
C007B-196161
Manufacturer No.
I355894-500μg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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8-iso Prostaglandin E|2|is the epimer at C8 of PGE2 and is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. This compound has been shown to be a potent renal vasoconstrictor in the rat, and to inhibit U-46619

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8-iso Prostaglandin E|2|is the epimer at C8 of PGE2 and is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. This compound has been shown to be a potent renal vasoconstrictor in the rat, and to inhibit U-46619 or I-BOP-induced platelet aggregation with IC|50|values of 0.5 and 5 μM, respectively. Interestingly it has been reported that this compound also relaxes smooth muscle and has been shown to cause vasodilation of porcine coronary artery. Furthermore, 8-iso Prostaglandin E|2|demonstrated brochodilation in porcine tracheal smooth muscle via K|+|current suppression caused by activation of thromboxane A2 receptors.

Molecular Formula: C20H32O5

Molecular Weight: 352.5

PubChem CID: 5283213

Isomeric SMILES: CCCCC[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@H]1C/C=C/CCCC(=O)O)O)O

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/I355894-SCI_cc179cbd01cf5f43a1e0036e72ff4483.pdf

UPC:
51131508
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
I355894-500μg
CAS:
27415-25-4
Product Size:
500μg
Hazard Statement Codes:
H361:H302
Precautionary Statement Codes:
P281:P270:P264:P202:P201

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