Application 6-Thio-2′:-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells. Biochem/physiol Actions 6-Thio-2′:-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that
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6-Thio-2′-Deoxyguanosine has been used in secreted luciferase enzyme activity in tonsillar cancer cells.
6-Thio-2′-deoxyguanosine (6-thio-dG) is a nucleoside analog and telomerase substrate that is incorporated into de novo–synthesized telomeres. 6-Thio-2′-deoxyguanosine induces telomere dysfunction and rapid cell death in cancer cells, while spearing telomerase-negative cells.
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