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6-azauracil

6-AZAURACIL

Catalog No.
C005B-041032
Manufacturer No.
A1757-5G
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
GR

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Application 6-Azauracil has been used as a transcriptional inhibitor to study its effects on the deletion of termination and polyadenylation protein (Tpa1) and Mag1 on cell viability. It has also been used as an orotidine-5′-monophosphate

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Application

6-Azauracil has been used as a transcriptional inhibitor to study its effects on the deletion of termination and polyadenylation protein (Tpa1) and Mag1 on cell viability. It has also been used as an orotidine-5′-monophosphate decarboxylase (OMPdecase) inhibitor in minimal media for determining the OMPdecase activity.

Biochem/physiol Actions

6-Azauracil (6-AU) is a pyrimidine analog of uracil and exhibits antitumor activity. It inhibits the growth of various microorganisms by depleting intracellular guanosine triphosphate (GTP) and uridine triphosphate (UTP) nucleotide pools.

Molecular Weight: 113.07. Empirical Formula: C3H3N3O2. Quality Level: 100. Assay: ≥. 98%. form: powder. mp: 274-275 . °C (lit.). solubility: 1 M NH4OH: 50 . mg/mL, clear to slightly hazy, colorless to light yellow-green. SMILES string: O: C1NN: CC(: O)N1. InChI: 1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8). InChI key: SSPYSWLZOPCOLO-UHFFFAOYSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.
UPC:
51141514
Condition:
New
HazmatClass:
No
MPN:
A1757-5G
CAS:
461-89-2

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