5-Methoxyquinolin-8-amine (C007B-224488)

8-Amino-5-methoxyquinoline is a substituted quinoline derivative that can be prepared using 5-chloro-2-nitroaniline as a starting material. It can act as an easily removable directing group and also mediate C-H activation. These properties have been useful for synthesizing isomeric dibenzoxazepinones and complex pyrrolidinones from compounds containing 8-amino-5-methoxyquinoline moiety.Application：The Chen auxiliary was reported to be an effective directing group in the synthesis of pyrrolidones from assisting in the activation of C(sp3)-H bonds and can be readily installed through amide bond formation and removed through mild conditions using CAN at room temperature.

Specifications and Purity: ≥97%

Molecular Formula: C10H10N2O

Molecular Weight: 174.2

PubChem CID: 777110

Isomeric SMILES: COC1=C2C=CC=NC2=C(C=C1)N

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