Application
Reactant for preparation of:
- Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP
- Cytotoxic and antimitotic agents
- Insulin-like growth factor 1 receptor inhibitors
- Antitumoral agents
- Factor Xa inhibitor
- Potential antivascular agents
- Gli1-mediated transcription in the Hedgehog pathway
- Inhibitors of receptor tyrosine kinase with antiangiogenic effects
- PKCθ inhibitors
- HIV protease inhibitors
Molecular Weight: 132.16. Empirical Formula: C
8H
8N
2. Quality Level: 100. Assay: 97%. form: crystals. mp: 131-133 . °C (dec.) (lit.). SMILES string: Nc1ccc2[nH]ccc2c1. InChI: 1S/C8H8N2/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H,9H2. InChI key: ZCBIFHNDZBSCEP-UHFFFAOYSA-N. Pictograms: GHS06,GHS09. Signal Word: Danger. Hazard Statements: H302 - H311 - H319 - H400. Precautionary Statements: P264 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Dermal. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.