4-Methylumbelliferone sodium salt is a selective inhibitor of Hyaluronan (HA) synthesis. HA is a major component in the metastasis of malignant tumors. Studies indicate that in the presence of 4-Methylumbelliferone sodium salt cell proliferation, migration, and growth are inhibited, while apoptosis is induced. In addition, the motility and cell growth was inhibited in fibroblast cell line NIH/3T3 . 4-Methylumbelliferone sodium salt is thought to function as an inhibitor via the depletion of UDP-glucuronic acid, the common substrate for HA synthesis. It is also believed that 4-Methylumbelliferone sodium salt can suppress the expression of HA-synthase.
Specifications and Purity: ≥98%
Molecular Formula: C10H7O3•Na
Molecular Weight: 198.15
PubChem CID: 3364573
Isomeric SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)[O-].[Na+]
Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/M347230-SCI_21825bd330578df701a802e3acb655ed.pdf
- UPC:
- 51111905
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- M347230-5g
- CAS:
- 5980-33-6
- Product Size:
- 5g
- Precautionary Statement Codes:
- P264
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