4-METHOXYPHENYLMAGNESIUM BROMIDE 0.5M SOLUTION IN TETRAHYDROFURAN (C005B-014560)

Application

4-Methoxyphenylmagnesium bromide is a general Grignard reagent that can be used:

• In the denickelation of porphyrins and to replace the metal center with magnesium.
• To synthesize a tubulin polymerization inhibitor, 2-Amino-3,4,5-trimethoxybenzophenone.
• In the total synthesis of (−)-centrolobine.

Molecular Weight: 211.34. Empirical Formula: C₇H₇BrMgO. linearFormula: CH₃OC₆H₄MgBr. reaction suitability: reaction type: Grignard Reaction. Quality Level: 100. concentration: 0.5 . M in THF. bp: 65-67 . °C. density: 0.955 . g/mL . at 25 . °C. SMILES string: COc1ccc([Mg]Br)cc1. InChI: 1S/C7H7O.BrH.Mg/c1-8-7-5-3-2-4-6-7. . /h3-6H,1H3. 1H. /q. . +1/p-1. InChI key: JKXAZEXIOPFJSC-UHFFFAOYSA-M. Pictograms: GHS02,GHS05,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H302 - H314 - H335 - H336 - H351. Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B. Supp Hazards: EUH014 - EUH018 - EUH019. Storage Class Code: 3 - Flammable liquids. WGK: WGK 3. Flash Point(F): -4.0 °F. Flash Point(C): -20 °C.