General description
4-Hydroxy-3-nitrocoumarin is a coumarin derivative and its cytotoxic action against cultured human tumor and normal cells has been investigated. It can be prepared by the nitration of 4-hydroxycoumarin in glacial acetic acid by using 72% HNO3.
Application
4-Hydroxy-3-nitrocoumarin may be used as starting reagent for the synthesis of following compounds:
- 4-chloro-3-nitrocoumarin
- 2-unsubstituted 3-nitrochromone
- 4-amino-3-nitrocoumarins
Molecular Weight: 207.14. Empirical Formula: C
9H
5NO
5. Quality Level: 100. Assay: 98%. mp: 172 . °C (dec.) (lit.). SMILES string: OC1: C(C(: O)Oc2ccccc12)[N+]([O-]): O. InChI: 1S/C9H5NO5/c11-8-5-3-1-2-4-6(5)15-9(12)7(8)10(13)14/h1-4,11H. InChI key: NZQAQAUWFHMVEM-UHFFFAOYSA-N. Pictograms: GHS06. Signal Word: Danger. Hazard Statements: H301. Precautionary Statements: P264 - P270 - P301 + P310 - P405 - P501. Hazard Classifications: Acute Tox. 3 Oral. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.