General description
4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P21/n.
Application
4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.
Used recently in the preparation of medicinally active benzo[b]furans and thiophenes.
Molecular Weight: 154.14. Empirical Formula: C8H7FO2. linearFormula: FC6H3(OH)COCH3. Quality Level: 100. Assay: 98%. mp: 31-35 . °C (lit.). SMILES string: CC(: O)c1ccc(F)cc1O. InChI: 1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3. InChI key: HLTBTUXAMVOKIH-UHFFFAOYSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H315 - H319 - H335. Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): 210.2 °F - closed cup. Flash Point(C): 99 °C - closed cup. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.- UPC:
- 51182008
- Condition:
- New
- HazmatClass:
- No
- MPN:
- 466964-5G
- CAS:
- 1481-27-2
akash.verma@cenmed.com
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