4-BROMOMETHYL-7-METHOXYCOUMARIN 97% (C005B-034734)

Application

4-Bromomethyl-7-methoxycoumarin has been used:

• as derivatization reagent in determination of 5-fluorouracil (5-FU) in human plasma by HPLC-tandem mass spectrometry
• as derivatization reagent in fluorescence detection of sodium monofluoroacetate (MFA-Na) in biological samples by HPLC
• in the synthesis of new caged derivatives of hydrolysis-resistant 8-bromoadenosine cyclic 3′,5′-monophosphate (8-Br-cAMP) and 8-bromoguanosine cyclic 3′,5′-monophosphate (8-Br-cGMP)
• in TLC and HPLC separation and fluorometric analysis of a wide range of naturally occurring acids, including bile and thromboxane B₂

Fluorescent label for fatty acids.

Molecular Weight: 269.09. Empirical Formula: C₁₁H₉BrO₃. Quality Level: 200. Assay: 97%. form: solid. mp: 213-215 . °C (lit.). solubility: chloroform: soluble 20 . mg/mL, clear, colorless to faintly yellow. fluorescence: λ. _ex . 322 . nm. λ. _em . 395 . nm (after derivatization). SMILES string: COc1ccc2C(CBr): CC(: O)Oc2c1. InChI: 1S/C11H9BrO3/c1-14-8-2-3-9-7(6-12)4-11(13)15-10(9)5-8/h2-5H,6H2,1H3. InChI key: CTENSLORRMFPDH-UHFFFAOYSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302 - H315 - H319 - H335. Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.