A23187 4-BROMO- 1PC X 1MG (C005B-077903)

General description

Brominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

Brominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

Application

Nonfluorescent Ca²⁺ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca²⁺ with fluorescent probes.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Cation ionophore

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Other Notes

Deber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.
Deber, C.M., et al. 1985. Anal. Biochem.146, 349.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Molecular Weight: 602.52. Empirical Formula: C₂₉H₃₆BrN₃O₆. Quality Level: 100. Assay: ≥. 90% (HPLC). form: solid. manufacturer/tradename: Calbiochem^®. . storage condition: OK to freeze, desiccated (hygroscopic), protect from light. color: yellow. solubility: DMSO: 100 . mg/mL. shipped in: ambient. storage temp.: 2-8°C. SMILES string: CNc1c(Br)cc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(: O)c5ccc[nH]5)nc2c1C(O): O. InChI: 1S/C29H36BrN3O6/c1-14-8-9-29(16(3)11-15(2)27(39-29)17(4)26(34)19-7-6-10-32-19)38-20(14)13-22-33-25-21(37-22)12-18(30)24(31-5)23(25)28(35)36/h6-7,10,12,14-17,20,27,31-32H,8-9,11,13H2,1-5H3,(H,35,36)/t14-,15-,16-,17-,20-,27+,29+/m1/s1. InChI key: LDXQFZZGVTWFCF-FHYGWRBKSA-N. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable.