(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC 50 s of >: 9, >:9 and between 8 and 9,
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(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor. (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC 50 s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2).Form:Solid.
Specifications and Purity: ≥95%
Molecular Formula: C93H134N10O24
Molecular Weight: 1776.11
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