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3-typ

3-TYP (C007B-299475)

Catalog No.
C007B-299475
Manufacturer No.
T414087-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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Information3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selectiveSIRT3inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively.TargetsSIRT3 (cell-free): SIRT1

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Information3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selectiveSIRT3inhibitor which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively.TargetsSIRT3 (cell-free); SIRT1 (cell-free); SIRT2 (cell-free) 16 nM; 88 nM; 92 nMIn vitroMelatonin-induced increases in deacetylated-SOD2 expression and SOD2 activity are significantly attenuated by 3-TYP in HepG2 cells exposed to Cd (cadmium).Cell Research(from reference)Cell lines：HepG2 cells Concentrations：50 μM Incubation Time：12 h.

Specifications and Purity: ≥99%

Molecular Formula: C7H6N4

Molecular Weight: 146.15

PubChem CID: 9833992

Isomeric SMILES: C1=CC(=CN=C1)C2=NNN=C2

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/T414087-SCI_3dac729fdcfd097907073dc491f5a2d3.pdf

UPC:
42202101
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
T414087-25mg
CAS:
120241-79-4
Product Size:
25mg

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