3-Maleimidopropionic Acid (C007B-209102)

N-Maleoyl-β-alanine (3- maleimide propionic acid) is an aliphatic N-substituted maleimide. It is one of the components of EC145 (a folate-targeted vinca alkaloid conjugate) stable solution used for pharmacokinetic study of rodents.N-Maleoyl-β-alanine (3- maleimide propionic acid, N -(2- carboxyethyl) maleimide) is a suitable reagent used in the following research:The biotin binding affinity of Avd (S16C) (avidin with single point mutation S16C) was decreased.As a side chain reaction agent, the trypsin peptide was modified, resulting in mass shift, indicating the presence of cysteine residues.Cysteine exposed by Xenopus oocytes was blocked in advance and used as an expression system to study the conformational changes of cASIC1a receptor.It can be used for the following research:As a protective agent for keratin fibers in high temperature process.As an unbreakable maleimide group in the synthesis process of four-walled molecular umbrella-octa-arginine conjugate.Synthesis of N-Maleoyl-β-Organotin Carboxylate-Alanine.Interaction between functionalized gold surface and cysteine modified peptide.Preparation of crosslinked dextran-polyethylene glycol hydrogel matrix.

Specifications and Purity: ≥97%

MDL Number: MFCD00043030

Molecular Formula: C7H7NO4

Molecular Weight: 169.13

PubChem CID: 573621

Isomeric SMILES: C1=CC(=O)N(C1=O)CCC(=O)O

Beilstein Registry Number: 1528952

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/M122235-SCI_bc78d66d2947826b4a5d8336fdb3c73b.pdf