(2-HYDROXYPROPYL)-ALPHA-CYCLODEXTRIN MS=0.6 (C005B-013554)

General description

(2-Hydroxypropyl)-α-cyclodextrin is a hydroxyalkyl derivative of cyclodextrin, which is generally used as a substitute of α-cyclodextrin for potential application in food, cosmetics and pharmaceutical industries. It may be used as a parenteral drug carrier on account of its attractive characteristics such as: a greater extent of solubility in water, high dissolution capacity for weakly soluble analytes, and low toxicity.

Application

• (2-Hydroxypropyl)-α-cyclodextrin can be used as a chiral selector to resolve tryptophan racemate by capillary electrophoresis.
• It can be used to synthesize biodegradable polyrotaxanes for fabricating blood-contacting devices.
• Co-polymer based on (2-hydroxypropyl)-α-cyclodextrin cross-linked with polyethylenimine can be used as a gene delivery vector.
• It can also be used as stabilizer for antibacterial iodine formulations, as it forms a stable inclusion complex with iodine and improves aqueous solubility.

form: powder. Quality Level: 100. optical activity: [α. ]20/D +125°, c :  . 1 in H₂O. mol wt: average M_w ~1,180. extent of labeling: 0.6 molar substitution. mp: 245 . °C (dec.) (lit.). Storage Class Code: 11 - Combustible Solids. WGK: WGK 1. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: Eyeshields, Gloves, type N95 (US).