2-CHLOROBENZALDEHYDE 99% (C005B-087275)

General description

2-Chlorobenzaldehyde undergoes alkynylation with phenylacetylene in the presence of catalytic ligands and dimethylzinc at 0°C to form binaphthyl-derived amino alcohols.

Application

2-Chlorobenzaldehyde has been used in generation of small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of β-ketoesters, aldehydes and thioureas.

Molecular Weight: 140.57. Empirical Formula: C₇H₅ClO. linearFormula: ClC₆H₄CHO. vapor density: 4.84 (vs air). Quality Level: 100. vapor pressure: 1.27 mmHg ( 50 °C). Assay: 99%. autoignition temp.: 746 . °F. refractive index: n20/D 1.566 (lit.). bp: 209-215 . °C (lit.). mp: 9-11 . °C (lit.). density: 1.248 . g/mL . at 25 . °C (lit.). SMILES string: [H]C(: O)c1ccccc1Cl. InChI: 1S/C7H5ClO/c8-7-4-2-1-3-6(7)5-9/h1-5H. InChI key: FPYUJUBAXZAQNL-UHFFFAOYSA-N. Pictograms: GHS05. Signal Word: Danger. Hazard Statements: H314. Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405. Hazard Classifications: Skin Corr. 1B. Storage Class Code: 8A - Combustible, corrosive hazardous materials. WGK: WGK 1. Flash Point(F): 206.6 °F - closed cup. Flash Point(C): 97 °C - closed cup. Personal Protective Equipment: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter.