Application
2-Chloroacetamidecan be used as a reactant to synthesize:
- 2-Amino-4-chloroquinolines via o-alkylation of 4-chloro-1H-quinolin-2-ones and subsequent Smiles rearrangement.
- 2-(Formylaryloxy)acetamides by reacting with hydroxybenzaldehydes in the presence of potassium carbonate as a base.
- Biarylamine derivatives via aluminum triflate-catalyzed direct amination of benzhydrols.
Molecular Weight: 93.51. Empirical Formula: C
2H
4ClNO. linearFormula: ClCH
2CONH
2. vapor pressure: 0.05 mmHg ( 20 °C). Quality Level: 300. Assay: ≥. 98%. form: powder. mp: 116-118 . °C (lit.). SMILES string: NC(: O)CCl. InChI: 1S/C2H4ClNO/c3-1-2(4)5/h1H2,(H2,4,5). InChI key: VXIVSQZSERGHQP-UHFFFAOYSA-N. Pictograms: GHS06,GHS08. Signal Word: Danger. Hazard Statements: H301 - H317 - H361f. Precautionary Statements: P202 - P261 - P264 - P280 - P301 + P310 - P302 + P352. Hazard Classifications: Acute Tox. 3 Oral - Repr. 2 - Skin Sens. 1. Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects. WGK: WGK 2. Flash Point(F): 338.0 °F. Flash Point(C): 170 °C. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.