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2-bromo-5-fluoropyridine

2-BROMO-5-FLUOROPYRIDINE 97%

Catalog No.
C005B-039262
Manufacturer No.
595675-5G
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
GR

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Application 2-Bromo-5-fluoropyridine can be used in the synthesis of the following: 5-fluoro-2-phenylpyridine via Suzuki coupling reaction with phenylboronic acid 5-fluoro-2-(p-tolyl)pyridine via Suzuki coupling reaction with p-tolylboronic acid It

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Application

2-Bromo-5-fluoropyridine can be used in the synthesis of the following:

  • 5-fluoro-2-phenylpyridine via Suzuki coupling reaction with phenylboronic acid
  • 5-fluoro-2-(p-tolyl)pyridine via Suzuki coupling reaction with p-tolylboronic acid
It can undergo palladium-catalyzed homo-coupling reaction to give the corresponding biaryl. It can also be employed in a palladium-catayzed α-arylation of esters leading to 4-pyridylcarboxypiperidines.

Molecular Weight: 175.99. Empirical Formula: C5H3BrFN. Quality Level: 100. Assay: 97%. bp: 80-83 . °C/44 . mmHg (lit.). mp: 30-31 . °C (lit.). SMILES string: Fc1ccc(Br)nc1. InChI: 1S/C5H3BrFN/c6-5-2-1-4(7)3-8-5/h1-3H. InChI key: UODINHBLNPPDPD-UHFFFAOYSA-N. Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302 - H315 - H319 - H335. Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): 163.4 °F - closed cup. Flash Point(C): 73 °C - closed cup. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.
UPC:
51131514
Condition:
New
HazmatClass:
No
MPN:
595675-5G
CAS:
41404-58-4

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