2,6-Di-O-methyl-β-cyclodextrin (DM-β-CD)

Solubility in water: 800 g / L (25 ° C), dissolved in methanol, ethanol, acetone, pyridine, DMSO, and THF.Heptakis(2,6-di-O-methyl)-β-cyclodextrin is a hydrophilic derivative of cyclodextrin that possesses the ability to effectively dissolve lipophilic drugs like steroid hormones, vitamins A, E, and K, etc. It can be utilized to increase the dissolution and bioavailability of weakly water-soluble pharmaceutical compounds.Complexes are more soluble in aqueous solution than the corresponding complexes of β-cyclodextrin; Stimulation of fatty acid synthesisReactant involved in:• Physicochemical studies of inclusion complexes• Probing diffusion and single molecule interactions with reconstituted membrane proteins• Interactions with micelles causing micellar rupture• Studying cellular transport, used as a cell penetration enhancer• Physicochemical and biopharmaceutical improvement of drugs particularly with solubilization and stability• Interactions with cholesterolHeptakis(2,6-di-O-methyl)-β-cyclodextrin may be used:• To measure the equilibrium constant of its complexes with various enantiomeric pairs of chiral nitroxides by electron paramagnetic resonance (EPR) spectroscopy.• To study the crystal structure of its complex with n-butyl acrylate and isobornyl acrylate using X-ray diffraction (XRD).• As a chiral selector to resolve amphetamine related drugs by capillary zone electrophoresis.

Specifictaions: ≥98%

Specification: MFCD00011616

MDL Number: C56H98O35

Molecular Formula: 1331.36

PubChem CID: 10171019

Isomeric SMILES: COC[C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)OC)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)OC)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)OC)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)OC)O[C@@H]7[C@H](O[C@@H]([C@@H]([C@H]7O)OC)O[C@@H]8[C@H](O[C@H](O2)[C@@H]([C@H]8O)OC)COC)COC)COC)COC)COC)COC)OC)O

Beilstein Registry Number: 1679140

Related Documents: https://ald-pub-files.oss-cn-shanghai.aliyuncs.com/aladdinsci/pdp/sds/1/D100520-SCI_2476c8b6e6170e21f97b8ad13e58f064.pdf