2,5-Dihydroxy-1,4-dithiane (C007B-108085)

1,4-Dithiane-2,5-diol undergoes bifunctional squaramide catalyzed sulfa-Michael/aldol cascade reaction with chalcones to afford trisubstituted tetrahydrothiophenes.It participates in diastereoselective [3+3] cycloaddition with azomethine imines catalyzed by 1,4-diazabicyclo[2.2.2]octane.It is a mercaptoacetaldehyde dimer and an efficient synthon for incorporating a thiol group to in situ generated nitroalkenes.1,4-Dithiane-2,5-diol was used in the synthesis of: · substituted tetrahydrothiophene derivatives; · 2-amino-3-(arylsulfonyl)thiophenes, potential antiviral and antitumor agents.

Specifications and Purity: ≥97%

MDL Number: MFCD00006659

Molecular Formula: C4H8O2S2

Molecular Weight: 152.24

EC Number: 254-751-6

PubChem CID: 98330

Isomeric SMILES: C1C(SCC(S1)O)O

Beilstein Registry Number: 104402

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