General description
2,4-Dichloro-6-methylpyrimidine undergoes double cross-coupling reaction with 2-(tributylstannyl)pyridine, followed by aldol condensation to yield 4-arylvinyl-2,6-di(pyridin-2-yl)pyrimidines. It reacts with 1H,1H,2H,2H-perfluorodecanethiol during fluorous synthesis of disubstituted pyrimidines.
Application
2,4-Dichloro-6-methylpyrimidine was used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine.
Molecular Weight: 163.00. Empirical Formula: C5H4Cl2N2. Quality Level: 100. Assay: 98%. form: solid. bp: 219 . °C (lit.). mp: 44-47 . °C (lit.). SMILES string: Cc1cc(Cl)nc(Cl)n1. InChI: 1S/C5H4Cl2N2/c1-3-2-4(6)9-5(7)8-3/h2H,1H3. InChI key: BTLKROSJMNFSQZ-UHFFFAOYSA-N. Pictograms: GHS05. Signal Word: Danger. Hazard Statements: H314. Precautionary Statements: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363. Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B. Storage Class Code: 8A - Combustible, corrosive hazardous materials. WGK: WGK 3. Flash Point(F): 235.4 °F - closed cup. Flash Point(C): 113 °C - closed cup. Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges.- UPC:
- 51101613
- Condition:
- New
- HazmatClass:
- Yes
- MPN:
- 144185-25G
- CAS:
- 5424-21-5
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