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19(20)-epdpe

19(20)-EpDPE (C007B-153627)

Catalog No.
C007B-153627
Manufacturer No.
E342833-25μg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin)

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EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids produces epoxides such as 14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been little studied compared to arachidonate epoxygenase metabolites. 19(20)-EpDPE is a DHA epoxygenase metabolite, that is derived via epoxidation of the ω-3 double bond of DHA. EDHF activity of 19(20)-EpDPE has not been determined. The epoxygenase metabolites of DHA have also been detected in a murine inflammation model.

Specifications and Purity: A solution in ethanol

Molecular Formula: C22H32O3

Molecular Weight: 344.5

PubChem CID: 17760645

Isomeric SMILES: CC(C)N1C=NC=C1C=O

UPC:
41113710
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
E342833-25μg
CAS:
183012-99-9
Product Size:
25μg

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