11-deoxy Prostaglandin E1 (C007B-134093)

11-deoxy Prostaglandin E1 (11-deoxy PGE1) is a synthetic analog of PGE1 . Early reports show that it is a selective agonist for the EP2 receptor but effective at much higher concentrations than PGE2. However, later studies show that it is a non-selective agonist of EP receptors and stimulates cAMP release in Jurkat cells with an EC|50|of 0.25 μM. 11-deoxy PGE1 exhibits selectively for the mouse EP3 receptor and is essentially equipotent to PGE1 at this receptor subtype. The K|i|values for binding to the mouse EP1, EP2, EP3, and EP4 receptors are 600, 45, 1.1, and 23 nM, respectively.

Specifications and Purity: ≥96%

Molecular Formula: C20H34O4

Molecular Weight: 338.48

PubChem CID: 5283055

Isomeric SMILES: CCCCC[C@@H](/C=C/[C@H]1CCC(=O)[C@@H]1CCCCCCC(=O)O)O

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