1-Benzhydrylpiperazine (C007B-037911)

1-(Diphenylmethyl)piperazine is an intermediate during drug synthesis. It has been reported to be formed during the oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] in rat liver microsomes.[1] It reacts with quinone in acetonitrile, followed by oxidation with an alkaline potassium ferricyanide, to afford 4-amino-3,6-di(tert-butyl)-o-benzoquinones.Application1-(Diphenylmethyl)piperazine [N-(Diphenylmethyl)piperazine] may be used for the synthesis of 2-nitro-3,4,4-trichloro-1-(propylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene and 2-nitro-3,4,4-trichloro-1-(octadecylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene.

Specifications and Purity: ≥98%(GC)

MDL Number: MFCD00038379

Molecular Formula: C17H20N2

Molecular Weight: 252.36

PubChem CID: 70048

Isomeric SMILES: C1CN(CCN1)C(C2=CC=CC=C2)C3=CC=CC=C3

Beilstein Registry Number: 222773

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/B134038-SCI_c23d51d9111b8c1aad2d28291e8c0914.pdf