1 2-DIMETHOXYETHANE REAGENTPLUS(R) =99% INHIBITOR-FREE (C005B-008121)

General description

1,2-Dimethoxyethane (DME) is an inert aprotic polar solvent for electrolytes of lithium batteries, polysilicones, oligo- and polysaccharides.

Application

1,2-Dimethoxyethane can be used as a solvent to synthesize:

• Oxazoles from α-acylamino ketones via Robinson-Gabriel reaction.
• 5-Arylhistidines via Suzuki-Miyaura cross-coupling between 5-bromohistidine and arylboronic acids.
• Aryl thioethers via Pd-catalyzed thioetherification of aryl halides with aliphatic and aromatic thiols.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Molecular Weight: 90.12. Empirical Formula: C₄H₁₀O₂. linearFormula: CH₃OCH₂CH₂OCH₃. vapor density: 3.1 (20 °C, vs air). Quality Level: 100. vapor pressure: 48 mmHg ( 20 °C). product line: ReagentPlus^®. . Assay: ≥. 99%. form: liquid. autoignition temp.: 396 . °F. expl. lim.: 10.4 . %. impurities: ≤. 0.5% (water). refractive index: n20/D 1.379 (lit.). pH: 7. bp: 85 . °C (lit.). mp: −. 58 . °C (lit.). density: 0.867 . g/mL . at 25 . °C (lit.). SMILES string: COCCOC. InChI: 1S/C4H10O2/c1-5-3-4-6-2/h3-4H2,1-2H3. InChI key: XTHFKEDIFFGKHM-UHFFFAOYSA-N. Pictograms: GHS02,GHS07,GHS08. Signal Word: Danger. Hazard Statements: H225 - H315 - H332 - H360FD. Precautionary Statements: P202 - P210 - P233 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P313. Hazard Classifications: Acute Tox. 4 Inhalation - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2. Supp Hazards: EUH019. Storage Class Code: 3 - Flammable liquids. WGK: WGK 1. Flash Point(F): 41.0 °F - closed cup. Flash Point(C): 5 °C - closed cup.