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1,2,3,4,5,6-hexabromocyclohexane

1,2,3,4,5,6-Hexabromocyclohexane (C007B-182996)

Catalog No.
C007B-182996
Manufacturer No.
H276112-25mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

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A cell-permeable hexabromocyclohexane compound that interacts with a solvent-accessible pocket near the activation loop of JAK2 and acts as a specific, reversible, and direct inhibitor of JAK2 autophosphorylation (maximal inhibition at 50 µM in

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A cell-permeable hexabromocyclohexane compound that interacts with a solvent-accessible pocket near the activation loop of JAK2 and acts as a specific, reversible, and direct inhibitor of JAK2 autophosphorylation (maximal inhibition at 50 µM in BSC-40 cells overexpressing JAK2). Reduces growth hormone-mediated JAK2 activation in γ2A cells that stably express growth hormone receptor and JAK2. Does not block EGFR autophosphorylation in murine fibroblasts.A cell-permeable, specific, reversible, and direct inhibitor of JAK2 autophosphorylation (maximal inhibition at 50 µM in BSC-40 cells overexpressing JAK2 that interacts with a solvent-accessible pocket near the activation loop of JAK2. Reduces growth hormone-mediated JAK2 activation in γ2A cells that stably express growth hormone receptor and JAK2. Does not block EGFR autophosphorylation in murine fibroblasts.

Specifications and Purity: ≥98%

Molecular Formula: C6H6Br6

Molecular Weight: 557.54

PubChem CID: 74603

Isomeric SMILES: C1(C(C(C(C(C1Br)Br)Br)Br)Br)Br

Related Documents: https://aladdin-for-icloud-store.oss-cn-hangzhou.aliyuncs.com/aladdinsci/pdp/sds/1/H276112-SCI_abfadba8b9d70a8cbb849cf66534654f.pdf

UPC:
51131514
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
H276112-25mg
CAS:
1837-91-8
Product Size:
25mg
Hazard Statement Codes:
H319:H302
Precautionary Statement Codes:
P501:P305+P351+P338:P301+P312:P330:P280:P270:P264

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