Rabbit anti Human NLK Antibody, Recombinant (R03-2K8), could be used for WB and so on.Application:WB: 1/500 - 1/1000 Protein FunctionRole in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity). Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.Post-translationalDually phosphorylated on Thr-303 and Tyr-305, which activates the enzyme.
Specifications and Purity: ExactAb™, Validated, Recombinant, 0.5 mg/mL
- UPC:
- 51201601
- Condition:
- New
- HazmatClass:
- No
- WeightUOM:
- LB
- MPN:
- Ab118223-50μl
- Product Size:
- 50μl
akash.verma@cenmed.com
(732) 447-1115





