General description
Reagent-cartridge Mitsunobu is a reagent cartridge for the Synple 2 Automated Synthesizer that enables the dehydrative coupling of primary alcohols and a variety of pronucleophiles. The cartridge contains all necessary reagents to perform the Mitsunobu transformation. The Synple platform eliminates the tedious removal of the Ph3PO byproduct.
Scale: up to 0.5 mmol
Compatible alcohols: primary, secondary
Compatible nucleophiles: phenols, carboxylic acids, tosyl amides, hydrazones, phthalimides
Cartridge contents:
- Supported triphenylphosphine
- DTBAD (di-tert-butyl azodicarboxylate)
- SCX (for purification)
- Supported carbonate (scavenger)
Learn more about the Synple automated synthesis platform.
Features and Benefits of Synple Platform
- Time savings - pre-installed protocols have been highly optimized, which obviates the need for the user′s own reaction development and optimization
- Easy to use - protocols are loaded by simply scanning the cartridge; does not requires any programming knowledge
- Safety - all chemicals are contained in the system, minimizing the user′s exposure
- Set-up reaction in less than 5 minutes
- Small footprint
- Plug & Play system - simple installation
- Reaction temperatures from 25 °C - 80 °C
- Cartridges available for many different reactions
- Prefilled with all required reagents
- RFID chip containing optimized reaction protocol
Other Notes
An integrated console for capsule-based, automated organic synthesis
Legal Information
Product of Synple Chem AG
- UPC:
- 41116013
- Condition:
- New
- HazmatClass:
- No
- MPN:
- SYNPLE-M001-1EA
akash.verma@cenmed.com
(732) 447-1115





