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nordihydroguaiaretic acid (c15-1244-201)

NORDIHYDROGUAIARETIC ACID >=97.0% HPLC (C005B-044836)

Catalog No.
C005B-044836
Manufacturer No.
74540-5G
Manufacturer Name
Sigma-Aldrich
Quantity
5
Unit of Measure
GR

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Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS). Application Nordihydroguaiaretic acid can be used: In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV

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General description

Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS).

Application

Nordihydroguaiaretic acid can be used:

  • In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV inhibition activity.
  • As a starting material in the synthesis of tetra-O-methylnordihydroguaiaretic acid.

Biochem/physiol Actions

Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure.

Other Notes

Inhibitor of broad bean lipoxygenase

Molecular Weight: 302.36. Empirical Formula: C18H22O4. linearFormula: [-CH(CH3)CH2C6H3-1,2-(OH)2]2. Quality Level: 100. Assay: ≥. 97.0% (HPLC). form: crystals. impurities: ≤. 2% water. mp: 184-186 . °C (lit.). SMILES string: CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2. InChI: 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3. InChI key: HCZKYJDFEPMADG-UHFFFAOYSA-N. Gene Information: mouse ... Alox12(11684). Pictograms: GHS07. Signal Word: Warning. Hazard Statements: H302 - H315 - H319 - H335. Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338. Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3. Target Organs: Respiratory system. Storage Class Code: 11 - Combustible Solids. WGK: WGK 3. Flash Point(F): Not applicable. Flash Point(C): Not applicable. Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves.
UPC:
12162208
Condition:
New
HazmatClass:
No
MPN:
74540-5G
CAS:
500-38-9

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