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9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals. It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.

A monohydroperoxy PUFA produced from arachidonic acid by 12-LO.

9(S)-HpOTrE is a monohydroperoxy PUFA produced by the action of 5-LO on &alpha-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions.

15(S)-HpEDE is a monohydroperoxy PUFA produced by the action of 15-LO on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).

A monohydroperoxy PUFA produced from arachidonic acid by 12-LO.

The predominant LO product of arachidonic acid formed in mammalian platelets enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 &microM.

5(S)-HpEPE is a monohydroperoxy PUFA produced by the action of 5-LO on EPA. It is metabolized to LTA5, a key intermediate in the formation of the 5-series leukotrienes. Alternatively, 5(S)-HpEPE is reduced to 5(S)-HEPE by peroxidases.

A monohydroperoxy PUFA produced from arachidonic acid by 12-LO.

12(S)-HpEPE is a monohydroperoxy PUFA produced by the action of 12-LO on EPA. Although the biological activities of 12(S)-HpEPE have not been well characterized, it is expected to behave similarly to 12(S)-HpETE.

9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.

15(S)-HpEDE is a monohydroperoxy PUFA produced by the action of 15-LO on eicosadienoic acid. Although the biological activities of 15(S)-HpEDE have not been well characterized, it is expected to behave similarly to 15(S)-HpETE (Catalog No. 44720).

9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.