A nonpeptide angiotensin II receptor antagonist which selectively and insurmountably inhibits the angiotensin II AT1 receptor subtype (Ki = 3.7 nM) a partial agonist of PPAR&gamma, activating the receptor to 25-30% of that produced by the full
A nonpeptide angiotensin II receptor antagonist which selectively and insurmountably inhibits the angiotensin II AT1 receptor subtype (Ki = 3.7 nM) a partial agonist of PPAR&gamma, activating the receptor to 25-30% of that produced by the full
A structural analog of capsaicin, which is the noxious active component of hot peppers of the Capsicum genus, and the amide of vanillylamine and oleic acid acts as an agonist at TRPV1, inducing desensitization analgesia in rat and mouse models of
A structural analog of capsaicin, which is the noxious active component of hot peppers of the Capsicum genus, and the amide of vanillylamine and oleic acid acts as an agonist at TRPV1, inducing desensitization analgesia in rat and mouse models of
A major hepatic metabolite of zearalenone that is a less potent agonist of estrogen receptors than the parent compound has pronounced effects on uterotropic activity, sperm motility, and preimplantation embryonic development.
A major hepatic metabolite of zearalenone that is a less potent agonist of estrogen receptors than the parent compound has pronounced effects on uterotropic activity, sperm motility, and preimplantation embryonic development.
An irreversible EGFR tyrosine kinase inhibitor that blocks ATP-dependent autophosphorylation of EGFR carrying the T790M mutation as well as an L858R mutation (IC<sub>50</sub> = 8 nM) effective in mouse models of lung cancer driven by EGFRT790M.
An irreversible EGFR tyrosine kinase inhibitor that blocks ATP-dependent autophosphorylation of EGFR carrying the T790M mutation as well as an L858R mutation (IC<sub>50</sub> = 8 nM) effective in mouse models of lung cancer driven by EGFRT790M.
A structural analog of capsaicin, which is the noxious active component of hot peppers of the Capsicum genus, and the amide of vanillylamine and oleic acid acts as an agonist at TRPV1, inducing desensitization analgesia in rat and mouse models of
A structural analog of capsaicin, which is the noxious active component of hot peppers of the Capsicum genus, and the amide of vanillylamine and oleic acid acts as an agonist at TRPV1, inducing desensitization analgesia in rat and mouse models of
One of the most thermally stable elastomeric materials available, Perfluoro is a family of perfluoroelastomer compounds designed to provide superior chemical resistance, and they offer a cost savings over similar o-rings such as Kalrez® 4079 and
One of the most thermally stable elastomeric materials available, Perfluoro is a family of perfluoroelastomer compounds designed to provide superior chemical resistance, and they offer a cost savings over similar o-rings such as Kalrez® 4079 and
One of the most thermally stable elastomeric materials available, Perfluoro is a family of perfluoroelastomer compounds designed to provide superior chemical resistance, and they offer a cost savings over similar o-rings such as Kalrez® 4079 and
One of the most thermally stable elastomeric materials available, Perfluoro is a family of perfluoroelastomer compounds designed to provide superior chemical resistance, and they offer a cost savings over similar o-rings such as Kalrez® 4079 and