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N159132-5g5-Norbornene-2,3-dicarboximide. -
N159132-500g5-Norbornene-2,3-dicarboximide. -
N159132-25g5-Norbornene-2,3-dicarboximide. -
N159132-100g5-Norbornene-2,3-dicarboximide. -
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M420827-1mlInformationMK-8617 MK-8617 is an orally active pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1 , 2 , 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.TargetsPHD1 (Cell-free assay): PHD2 (Cell-free -
M420400-1mlMK-8245 is an liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Phase 2. -
M414011-5mgInformationMK-8617 is an pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1 , 2 , 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.TargetsPHD1 (Cell-free assay): PHD2 (Cell-free assay): PHD3 (Cell-free -
M414011-50mgInformationMK-8617 is an pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1 , 2 , 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.TargetsPHD1 (Cell-free assay): PHD2 (Cell-free assay): PHD3 (Cell-free -
M414011-25mgInformationMK-8617 is an pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1 , 2 , 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.TargetsPHD1 (Cell-free assay): PHD2 (Cell-free assay): PHD3 (Cell-free -
M414011-10mgInformationMK-8617 is an pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1 , 2 , 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.TargetsPHD1 (Cell-free assay): PHD2 (Cell-free assay): PHD3 (Cell-free -
M414011-100mgInformationMK-8617 is an pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1 , 2 , 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.TargetsPHD1 (Cell-free assay): PHD2 (Cell-free assay): PHD3 (Cell-free
