Test kits for radioimmunotherapy

A full antagonist of RXR that demonstrates potent, nanomolar binding affinity does not affect the corepressor interaction capacity of the RAR&alpha subunit in the RAR-RXR heterodimer configuration.

A non-steroidal androgen receptor antagonist (IC50 = 36 nM) reduces the efficiency of nuclear translocation of the androgen receptor and impairs both its binding to DNA and the recruitment of coactivators.

A selective inhibitor of diacylglycerol lipase (IC₅₀ = 4 &microM) that demonstrates relatively weak inhibition of phospholipases A2 and C elevates the concentration of diacylglycerol, which leads to activation of PKC.

A potent, selective inhibitor of all three JNK isoforms (Ki values range from 25 to 50 nM) bioavailable when delivered by gavage, blocking JNK signaling and renal fibrosis in a rat obstructed kidney model decreases hepatic necrosis and apoptosis

A selective inhibitor of NUAK1 and NUAK2 (IC₅₀s = 20 and 100 nM, respectively) inhibits the phosphorylation of the NUAK1 substrate MYPT1 at Ser445 inhibits proliferation and migration of mouse embryonic fibroblasts and U2OS cells at 10

A selective inhibitor of the MAP kinases p38&alpha (IC₅₀ = 3.2 nM) and p38&beta (IC₅₀ = 122 nM) has no inhibitory effect against a panel of other kinases when tested in vitro at 50 &muM orally active, significantly

A non-steroidal androgen receptor antagonist (IC50 = 36 nM) reduces the efficiency of nuclear translocation of the androgen receptor and impairs both its binding to DNA and the recruitment of coactivators.

A selective inhibitor of diacylglycerol lipase (IC₅₀ = 4 &microM) that demonstrates relatively weak inhibition of phospholipases A2 and C elevates the concentration of diacylglycerol, which leads to activation of PKC.

Unassembled component kits offer the convenience of one product number for the vial, cap, and septa. Components are packaged to work with the unique MicroLiter Dispenser.

Unassembled component kits offer the convenience of one product number for the vial, cap, and septa. Components are packaged to work with the unique MicroLiter Dispenser.

Unassembled component kits offer the convenience of one product number for the vial, cap, and septa. Components are packaged to work with the unique MicroLiter Dispenser.

PosiTector&reg SST Soluble Salt Tester for measuring the concentration of soluble salts on metal surfaces. Important Features: *Intuitive step-by-step interface guides users through the Bresle Method *Onscreen timer to report test duration