akash.verma@cenmed.com
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70735-5A structural homolog of rosiglitazone that binds PPAR&gamma with about 1/10 the affinity of rosiglitazone yet is a more potent antidiabetic agent in whole animal experiments than rosiglitazone (ED<sub>50</sub>s = 2.7 mg/kg and 7. -
16424-5A selective antagonist of BET bromodomains, binding with 10-100-fold higher affinity for BD2 (IC<sub>50</sub> = 0.04-0. -
16442-15-trans U-44069 is the C-5 double bond isomer of U-44069. There are no published reports on its biological activities. -
18776-1A potent inhibitor of B-RafV600E (Kd = 14 nM in an in vitro binding assay) blocks B-RafV600E&ndashdependent phosphorylation of MEK in human melanoma A375 and colorectal cancer COLO 205 cells (IC<sub>50</sub>s = 78 and 60 nM, respectively) -
10008907-10A small-molecule agonist of GPR40 (EC50 = 47 nM) and GPR120 (EC50 = 2.2 µM), GPCRs that are activated by medium and long-chain fatty acids potentiates glucose-stimulated insulin secretion and the KCl-mediated increase in insulin secretion in -
70600-10REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC<sub>50</sub> value of 0.12 µM. -
16424-1A selective antagonist of BET bromodomains, binding with 10-100-fold higher affinity for BD2 (IC<sub>50</sub> = 0.04-0. -
70735-1A structural homolog of rosiglitazone that binds PPAR&gamma with about 1/10 the affinity of rosiglitazone yet is a more potent antidiabetic agent in whole animal experiments than rosiglitazone (ED<sub>50</sub>s = 2.7 mg/kg and 7. -
10008907-5A small-molecule agonist of GPR40 (EC50 = 47 nM) and GPR120 (EC50 = 2.2 µM), GPCRs that are activated by medium and long-chain fatty acids potentiates glucose-stimulated insulin secretion and the KCl-mediated increase in insulin secretion in -
70600-5REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC<sub>50</sub> value of 0.12 µM. -
BM7C-2000-582B-582 BradyGlo⢠is a glow-in-the-dark pressure sensitive polyester. Ideal for use in exit and directional signs, identification of fire alarms and extinguishers, and directional systems for escape or evacuations routes." -
BM7C-1000-582B-582 BradyGlo⢠is a glow-in-the-dark pressure sensitive polyester. Ideal for use in exit and directional signs, identification of fire alarms and extinguishers, and directional systems for escape or evacuations routes."
