An irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases at 20-200 µM arrests human epidermoid carcinoma A431 cells at mitotic metaphase inhibits protease-resistant protein accumulation in scrapie-infected
An irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases at 20-200 µM arrests human epidermoid carcinoma A431 cells at mitotic metaphase inhibits protease-resistant protein accumulation in scrapie-infected
A natural phytochemical with anti-inflammatory effects inhibits the growth of leukemia cells (IC<sub>50</sub> = 1.5 &mug/ml), inducing apoptosis at 15 &muM, suppresses STAT3-regulated gene expression and prevents angiogenesis.
A natural phytochemical with anti-inflammatory effects inhibits the growth of leukemia cells (IC<sub>50</sub> = 1.5 &mug/ml), inducing apoptosis at 15 &muM, suppresses STAT3-regulated gene expression and prevents angiogenesis.
An orally bioavailable, blood-brain barrier permeable complex used in cellular imaging experiments to selectively label hypoxic tissue improves locomotor function and survival in a transgenic ALS mouse model by delivering copper specifically to
An orally bioavailable, blood-brain barrier permeable complex used in cellular imaging experiments to selectively label hypoxic tissue improves locomotor function and survival in a transgenic ALS mouse model by delivering copper specifically to
A potent, selective inhibitor of Hsp90&beta (IC<sub>50</sub> = 58 nM) inhibits proliferation (GI<sub>50</sub>s from 53 to 190 nM) or induces cell death in cancer cell lines orally available and has antitumor effects in human tumor xenografts in
A potent, selective inhibitor of Hsp90&beta (IC<sub>50</sub> = 58 nM) inhibits proliferation (GI<sub>50</sub>s from 53 to 190 nM) or induces cell death in cancer cell lines orally available and has antitumor effects in human tumor xenografts in
A potent dual inhibitor of PI3K and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anti-cancer agents when used in in vivo combination studies inhibits PI3K isoforms and mutants
A potent dual inhibitor of PI3K and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anti-cancer agents when used in in vivo combination studies inhibits PI3K isoforms and mutants
A potent dual inhibitor of PI3K and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anti-cancer agents when used in in vivo combination studies inhibits PI3K isoforms and mutants
A potent dual inhibitor of PI3K and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anti-cancer agents when used in in vivo combination studies inhibits PI3K isoforms and mutants
Gamma irradiation provides a method for complete viral and mycoplasma deactivation while maintaining the biological activity of the final product. Uses: Virus and vaccine production, projects needing a minimized risk of virus and mycoplasma
Gamma irradiation provides a method for complete viral and mycoplasma deactivation while maintaining the biological activity of the final product. Uses: Virus and vaccine production, projects needing a minimized risk of virus and mycoplasma
MCP-3, CCL7, murine (mouse): Murine CCL7, also known as MARC, is belonging to the CC chemokine family. It is encoded by the gene CCL7 and was isolated from a mouse mast cell line after Fc epsilon RI triggering by IgE plus antigen.
MCP-3, CCL7, murine (mouse): Murine CCL7, also known as MARC, is belonging to the CC chemokine family. It is encoded by the gene CCL7 and was isolated from a mouse mast cell line after Fc epsilon RI triggering by IgE plus antigen.