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Lisaftoclax (C007B-364768)

Catalog No.
C007B-364768
Manufacturer No.
L650177-5mg
Manufacturer Name
Aladdin Scientific
Quantity
1
Unit of Measure
EA

Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC 50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl , respectivelyIn VitroLisaftoclax (compound 6)

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Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC 50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl , respectivelyIn VitroLisaftoclax (compound 6) exhibits IC 50 values of 5.5 nM and 6.4 nM in Bcl-2 dependent RS4;11 cells and Bcl-xl dependent Molm13 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.Form:SolidIC50& Target:Bcl-2 2 nM (IC 50 ) Bcl-xL 5.9 nM (IC 50 ).

Specifications and Purity: ≥99%

Molecular Formula: C45H48ClN7O8S

Molecular Weight: 882.42

PubChem CID: 137355972

Isomeric SMILES: C1CC2(C1)CCC(=C(C2)C3=CC=C(C=C3)Cl)CN4CCN(CC4)C5=CC(=C(C=C5)C(=O)NS(=O)(=O)C6=CC(=C(C=C6)NC[C@H]7COCCO7)[N+](=O)[O-])OC8=CN=C9C(=C8)C=CN9

UPC:
85121808
Condition:
New
HazmatClass:
No
WeightUOM:
LB
MPN:
L650177-5mg
CAS:
2180923-05-9
Product Size:
5mg

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