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InformationA-381393 is a potent, selective, brain-penetrate antagonist of dopamine D4 receptor with Ki of 1.5 nM, 1.9 nM and 1.6 nM for human dopamine D4.4, D4.2 and D4.7 receptor, respectively. A-381393 shows moderate affinity for 5-HT2A with Ki of

InformationA-381393 is a potent, selective, brain-penetrate antagonist of dopamine D4 receptor with Ki of 1.5 nM, 1.9 nM and 1.6 nM for human dopamine D4.4, D4.2 and D4.7 receptor, respectively. A-381393 shows moderate affinity for 5-HT2A with Ki of

InformationA-381393 is a potent, selective, brain-penetrate antagonist of dopamine D4 receptor with Ki of 1.5 nM, 1.9 nM and 1.6 nM for human dopamine D4.4, D4.2 and D4.7 receptor, respectively. A-381393 shows moderate affinity for 5-HT2A with Ki of

InformationA-381393 is a potent, selective, brain-penetrate antagonist of dopamine D4 receptor with Ki of 1.5 nM, 1.9 nM and 1.6 nM for human dopamine D4.4, D4.2 and D4.7 receptor, respectively. A-381393 shows moderate affinity for 5-HT2A with Ki of

AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor.

AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor.

AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor.

AM1172 is metabolically stable anandamide uptake inhibitor and FAAH inhibitor.

Potent and selective TRPM8 antagonist: activein vivo.

Potent and selective TRPM8 antagonist: activein vivo.

Potent and selective TRPM8 antagonist: activein vivo.

Potent and selective TRPM8 antagonist: activein vivo.