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InformationSAR-20347 is a potent inhibitor ofTYK2,JAK1,JAK2andJAK3with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediatedIL-12andIFN-αsignaling.TargetsIL-12 : IFN-α : TYK2 (Cell-free assay): JAK1

InformationSAR-20347 is a potent inhibitor ofTYK2,JAK1,JAK2andJAK3with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediatedIL-12andIFN-αsignaling.TargetsIL-12 : IFN-α : TYK2 (Cell-free assay): JAK1

SD-06.

SD-06.

SD-06.

Biochemical Test:SDS-PAGE (purity&gt: 90%): Western blot with i: Ro/SS-A (52 kDa) autoantibody-positive sample: ii: monoclonal anti-His-tag antibody.Calculated Isoelectric Point:pH 6.15Coating Concentration:0.3-0.65 µg/ml (depending on the type of

Biochemical Test:SDS-PAGE (purity&gt: 90%): Western blot with i: Ro/SS-A (52 kDa) autoantibody-positive sample: ii: monoclonal anti-His-tag antibody.Calculated Isoelectric Point:pH 6.15Coating Concentration:0.3-0.65 µg/ml (depending on the type of

PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM.

PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM.

PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM.

Potent WDR5/MLL interaction inhibitor.

Potent WDR5/MLL interaction inhibitor.