Contains a collection of small, drug-like molecules that inhibit or antagonize epigenetic readers, writers, and erasers each packaged as a 2 mg sample size for ease of preclinical target validation during early stages of drug discovery.
Contains a collection of small, drug-like molecules that inhibit or antagonize epigenetic readers, writers, and erasers each packaged as a 2 mg sample size for ease of preclinical target validation during early stages of drug discovery.
A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.
A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.
An orally bioavailable, selective inhibitor of EZH2 (Ki = 2.5 nM) blocks H3K27 trimethylation in both wild-type and mutant lymphoma cells (IC<sub>50</sub>s range from 2-90 nM) induces apoptosis and differentiation specifically in SMARCB1-deleted
An orally bioavailable, selective inhibitor of EZH2 (Ki = 2.5 nM) blocks H3K27 trimethylation in both wild-type and mutant lymphoma cells (IC<sub>50</sub>s range from 2-90 nM) induces apoptosis and differentiation specifically in SMARCB1-deleted
A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.
A hybrid molecule of an H2S donor and the NSAID indomethacin that does not cause gastric damage or promote leukocyte adherence to vascular endothelium.
A cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK (IC<sub>50</sub> = 230 nM) poorly inhibits PI3K (IC<sub>50</sub> = 13 µM) and is inactive against ATM, ATR, and PARP-1.
A cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK (IC<sub>50</sub> = 230 nM) poorly inhibits PI3K (IC<sub>50</sub> = 13 µM) and is inactive against ATM, ATR, and PARP-1.
MicroLiter septa for 16mm Screwthread Headspace Vials are constructed of PTFE, PTFE/butyl, or PTFE/silicone to suit a variety of chromatography applications.
MicroLiter septa for 16mm Screwthread Headspace Vials are constructed of PTFE, PTFE/butyl, or PTFE/silicone to suit a variety of chromatography applications.