akash.verma@cenmed.com
(732) 447-1115-
SML1806-25MGBiochem/physiol Actions YU142670 is a selective inhibitor against OCRL1/INPP5F (IC50 = 0.71 μ:M: substrate = PI(4,5)P2) and OCRL2/INPP5B (IC50 = 0. -
SML1806-5MGBiochem/physiol Actions YU142670 is a selective inhibitor against OCRL1/INPP5F (IC50 = 0.71 μ:M: substrate = PI(4,5)P2) and OCRL2/INPP5B (IC50 = 0. -
SML2264-25MGBiochem/physiol Actions Col003 is a cell penetrant, selective and potent inhibitor of the interaction of Hsp47 with collagen. It binds to the collagen binding site on Hsp47. -
SML2264-5MGBiochem/physiol Actions Col003 is a cell penetrant, selective and potent inhibitor of the interaction of Hsp47 with collagen. It binds to the collagen binding site on Hsp47. -
SML2273-25MGBiochem/physiol Actions KUNB31 is an isoform-selective inhibitor of Hsp90β: with an IC50 value of 180 nM and >: 50-fold selectivity over closely related isoforms Hsp90α: and GRP94.Hsp90 inhibitors currently in clinical trials are all -
SML2273-5MGBiochem/physiol Actions KUNB31 is an isoform-selective inhibitor of Hsp90β: with an IC50 value of 180 nM and >: 50-fold selectivity over closely related isoforms Hsp90α: and GRP94.Hsp90 inhibitors currently in clinical trials are all -
SML2694-25MGBiochem/physiol Actions FB23-2 can also prevent osteogenic differentiation of human mesenchymal stem cells (MSCs). It is capable of delaying leukemogenesis in vivo . -
SML2694-5MGBiochem/physiol Actions FB23-2 can also prevent osteogenic differentiation of human mesenchymal stem cells (MSCs). It is capable of delaying leukemogenesis in vivo . -
SML2981-25MGBiochem/physiol Actions EN219 is a cell-permeable chloroacetamide compound that selectively inhibits E3 ligase RNF114-mediated autoubiquitination and p21 ubiquitination. EN219 is shown to covalently interact with RNF114-C8 (IC50 = 470 nM), -
SML2981-5MGBiochem/physiol Actions EN219 is a cell-permeable chloroacetamide compound that selectively inhibits E3 ligase RNF114-mediated autoubiquitination and p21 ubiquitination. EN219 is shown to covalently interact with RNF114-C8 (IC50 = 470 nM), -
SML2994-25MGBiochem/physiol Actions HQ461 is a CDK12 kinase domain-targeting molecular glue that promotes CDK12 interaction with DDB, resulting in DDB1-CUL4-RBX1 E3 ubiquitin ligase complex-mediated CDK12-interacting protein cyclin K (CycK) polyubiquitination -
SML2994-5MGBiochem/physiol Actions HQ461 is a CDK12 kinase domain-targeting molecular glue that promotes CDK12 interaction with DDB, resulting in DDB1-CUL4-RBX1 E3 ubiquitin ligase complex-mediated CDK12-interacting protein cyclin K (CycK) polyubiquitination
